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Structural MRI and Diffusion Tensor Imaging (DTI) in Asperger Sydrome (MRC-AIMS study)
Mike Lombardo, Bhismadev Chakrabarti, Simon Baron-Cohen, Sally Wheelwright, Susan Sadek, Greg Pasco, Ed Bullmore, John Suckling, Declan Murphy, Patrick Bolton, Meng-Chuan Lai, AIMS Consortium
The ARC and the Brain Mapping Unit are the Cambridge node of a multi-centre study of neuroanatomy in autism, called the MRC AIMS (Autism Imaging Multicentre Study). The other two centres are London (Institute of Psychiatry, MRC AIMS Project Director Prof Declan Murphy) and Oxford (with collaborator Prof Tony Bailey). This project is scanning 100 adults with Asperger Syndrome or high functioning autism and 100 age-matched controls (all male) to measure cortical thickness, major tracts (using DTI) and volumetric differences in defined brain regions (using structural MRI).
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