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Early screening for autism at 18 months
Carrie Allison, Simon Baron-Cohen, Sally Wheelwright, Carol Brayne, Tony Charman, Fiona Scott, Jo Williams, Patrick Bolton, Rick Griffin, Greg Pasco, Rachel Jackson, Jillian Sullivan

The ARC pioneered early screening for autism at 18 months of age, using the CHAT (Checklist for Autism in Toddlers). This focused particularly on the absence of key behaviours (pretend play and joint attention) at 18 months of age as early indicators of a later diagnosis of autism. Whilst failure on the CHAT was found to be strongly predictive of later autism, the CHAT missed many cases of later autism spectrum conditions, particularly Asperger Syndrome, reflecting the fact that the CHAT was developed in the early 1990s when Asperger Syndrome was less well known. Our current work has revised the CHAT to make it quantitative (the Q-CHAT) in an effort to improve the sensitivity of the instrument.

We are also looking at developmental trajectories in at-risk toddlers with autism, specific language impairment (SLI), and learning difficulties, relative to typically developing toddlers.



References:



379
C. Allison, J. Williams, F. Scott, C. Stott, P. Bolton, S. Baron-Cohen and C. Brayne, (2007)
The Childhood Asperger Syndrome Test (CAST): Test-retest reliability in a high scoring sample
Autism 11(2):177-189
204
T. Charman, S. Baron-Cohen, J. Swettenham, A. Cox, G. Baird and A. Drew, (2003)
Predicting language outcome in infants with autism and pervasive development disorder
International Journal of of Language and Communication Disorders 38(3):265-285
167
G. Baird, T. Charman, A. Cox, S. Baron-Cohen, J. Swettenham, S. Wheelwright and A. Drew, (2001)
Screening and surveillance for autism and pervasive developmental disorders
Archives of Disease in Childhood 84:468-475
147
S. Baron-Cohen, S. Wheelwright, A. Cox, G. Baird, T. Charman, J. Swettenham, A. Drew and P. Doehring, (2000)
Checklist for Autism in Toddlers (CHAT)
Journal of Developmental and Learning Disorders 
82
S. Baron-Cohen, A. Cox, G. Baird, J. Swettenham, A. Drew, N. Nightingale, K. Morgan and T. Charman, (1996)
Psychological markers of autism at 18 months of age in a large population
British Journal of Psychiatry 168:158-163
25
S. Baron-Cohen, J. Allen and C. Gillberg, (1992)
Can autism be detected at 18 months? The needle, the haystack, and the CHAT
British Journal of Psychiatry 161:839-843


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