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Prevalence of autism spectrum conditions in primary schools (CAST)
Carrie Allison, Jo Williams, Fiona Scott, Carol Brayne, Patrick Bolton, Simon Baron-Cohen, Fiona Matthews, Angelica Ronald, Robert Plomin
We developed the CAST, formerly known as the Childhood Asperger Screening Test but renamed as the Childhood Autism Spectrum Test. The change of name reflects that it was originally designed for a prevalence study of Asperger Syndrome in childhood but is useful for low-functioning children too. We found that the CAST discriminates cases from controls well, and that CAST scores show strong heritability in a twin study. We have recently used the CAST as an instrument in a large population study in which 20,000 primary school age children in Cambridgeshire were sent the screen. Results will be available during 2008 but broadly confirm recent studies from other prevalence studies that autism spectrum conditions are found in about 1% of the population.
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References:

379 C. Allison, J. Williams, F. Scott, C. Stott, P. Bolton, S. Baron-Cohen and C. Brayne, (2007) The Childhood Asperger Syndrome Test (CAST): Test-retest reliability in a high scoring sample Autism 11(2):177-189
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346 A. Ronald, F. Happé, P. Bolton, L. M. Butcher, T. S. Price, S. Wheelwright, S. Baron-Cohen and R. Plomin, (2006) Genetic heterogeneity between the three components of the autism spectrum: a twin study Journal of the American Academy of Child & Adolescent Psychiatry 45:691-699
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230 J. Williams, F. Scott, C. Stott, C. Allison, P. Bolton, S. Baron- Cohen and C. Brayne, (2005) The CAST (Childhood Asperger Syndrome Test) : test accuracy Autism :45-68
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188 F. Scott, S. Baron-Cohen, P. Bolton and C. Brayne, (2002) Prevalence of autism spectrum conditions in children aged 5-11 years in Cambridgeshire, UK Autism 6(3):231-237
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175 F. Scott, S. Baron-Cohen, P. Bolton and C. Brayne, (2002) The CAST (Childhood Asperger Syndrome Test) : Preliminary development of UK screen for mainstream primary-school children Autism 6(1):9-31
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